Joris Hemelaar
BM BCh (Oxon) BSc (Hons) MSc PGDip DPhil (Oxon) MRCOG
Associate Professor
- Honorary Consultant Obstetrician, Oxford University Hospital NHS Foundation Trust
- Associate Editor, Frontiers in Microbiology
- Principal Investigator
- Associate Professor
Dr Hemelaar’s research focuses on the association of maternal HIV infection and antiretroviral therapy with adverse perinatal outcomes, such as preterm birth and low birthweight. The aims are to accurately estimate the burden of adverse pregnancy outcomes associated with maternal HIV infection and antiretroviral therapies, and to elucidate the mechanisms underlying these pathologies, with a view to developing predictive, preventative and interventional strategies.
A second line of research concerns the global molecular epidemiology of HIV-1. Global HIV-1 genetic diversity and evolution form a major challenge to treatment and prevention efforts and impacts HIV transmission, pathogenesis, diagnosis, and treatment. Global HIV diversity forms a major obstacle to HIV vaccine development. He conducts large studies to determine the global spread of HIV strains, which is crucial for the design, testing and deployment of HIV vaccines.
Dr Hemelaar obtained his BSc and MSc (cum laude) in Molecular Biology and Genetics at Leiden University, The Netherlands (1997). He then completed a DPhil in Molecular Immunology with Prof Sir Andrew McMichael FRS at the Weatherall Institute of Molecular Medicine and Trinity College, Oxford (2001).
This was followed by post-doctoral research at the Harvard Medical School, Boston, USA. He obtained his BM BCh medical degree at Magdalen College, Oxford (2007) and completed his Specialty Training in Obstetrics and Gynaecology in 2019, during which time he was an Academic Clinical Fellow and Clinical Lecturer in Oxford. In 2021 he was appointed as Senior Clinical Research Fellow in the National Perinatal Epidemiology Unit (NPEU) and Honorary Consultant Obstetrician at the John Radcliffe Hospital.
Recent publications
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Global and regional genetic diversity of HIV-1 in 2010-21: systematic review and analysis of prevalence.
Journal article
Nair M. et al, (2024), Lancet Microbe
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Perinatal outcomes associated with pre-exposure prophylaxis for HIV prevention during pregnancy: a systematic review and meta-analysis
Journal article
Erlwanger A. et al, (2024), eClinicalMedicine, 102532 - 102532
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Comparative risk of adverse perinatal outcomes associated with classes of antiretroviral therapy in pregnant women living with HIV: systematic review and meta-analysis.
Journal article
Beck K. et al, (2024), Front Med (Lausanne), 11
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Predicting risk of preterm birth in singleton pregnancies using machine learning algorithms.
Journal article
Yu Q-Y. et al, (2024), Front Big Data, 7
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Publisher Correction: Adverse perinatal outcomes attributable to HIV in sub-Saharan Africa from 1990 to 2020: systematic review and meta-analyses.
Journal article
Murray C. et al, (2023), Commun Med (Lond), 3