Kimenyi KM., Akinyi MY., Mwikali K., Gilmore T., Mwangi S., Omer E., Gichuki B., Wambua J., Njunge J., Obiero G., Bejon P., Langhorne J., Abdi A., Ochola-Oyier LI.

BACKGROUND: Cumulative malaria parasite exposure in endemic regions often results in the acquisition of partial immunity and asymptomatic infections. There is limited information on how host-parasite interactions mediate the maintenance of chronic symptomless infections that sustain malaria transmission. METHODS: Here, we determined the gene expression profiles of the parasite population and the corresponding host peripheral blood mononuclear cells (PBMCs) from 21 children (

Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected.

Kimenyi KM., Akinyi MY., Mwikali K., Gilmore T., Mwangi S., Omer E., Gichuki B., Wambua J., Njunge J., Obiero G., Bejon P., Langhorne J., Abdi A., Ochola-Oyier LI.

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