Emerging Monkeypox Virus Sublineage C.1 Causing Community Transmission, Vietnam, 2023.

Hoa HTT., Dung NT., Hung LM., Hong NTT., Quy VT., Thao NT., Duy NT., Truong H., Hoang TM., Thanh NT., Phuoc MPH., Trung TN., Thong NN., Huy ND., Thoa VTK., Vuong VT., Tai NT., Nhung HK., Linh DP., Thoa PTN., Yen LM., Thien TB., Truc THC., Thanh LK., Ny NTH., Hoang VT., Ngoc NM., Man DNH., Thwaites L., Thanh TT., Chau NVV., Thwaites G., Anh NT., Van Tan L.

We studied a community cluster of 25 mpox cases in Vietnam caused by emerging monkeypox virus sublineage C.1 and imported into Vietnam through 2 independent events; 1 major cluster carried a novel APOBEC3-like mutation. Three patients died; all had advanced HIV co-infection. Viral evolution and its potential consequences should be closely monitored.

DOI

10.3201/eid3011.240729

Type

Journal article

Journal

Emerg Infect Dis

Publication Date

11/2024

Volume

30

Pages

2385 - 2390

Keywords

HIV co-infection, Vietnam, genetic changes, monkeypox virus, mpox, sexually transmitted infections, sublinear C1, viruses, Vietnam, Humans, Mpox (monkeypox), Monkeypox virus, Male, Phylogeny, Female, Adult, Middle Aged, Communicable Diseases, Emerging, HIV Infections, History, 21st Century, Mutation, Coinfection

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