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Genetic substructure in Latin American individuals reveals novel associations, mechanistic insights, and variable polygenic risk score transferability for alcohol traits

Montalvo-Ortiz J., Martínez-Magaña J., Brito DA., Trichia E., Rivera-Hernández M., Porras L., Sullivan K., Jacobson D., Kember R., Nuñez D., Torres J., Peterson R., Zhou H., Vlot A., Merlet J., Townsend A., Wells A., Alvarez C., Lane M., Alegre-Díaz J., Berumen J., Kuri-Morales P., Tapia-Conyer R., Emberson J., Kranzler H., Justice A., Gelernter J., Sanchez-Roige S., Wassertheil-Smoller S., Perreira K., Daviglus M., Nicolini H., Genis-Mendoza A., Villatoro-Velazquez J., Medina-Mora M., Bustos-Gamiño M., Belangero S., Santoro M., Rohde L., Bressan R., Miguel E., Pan P., Salum G., Tucker K., Ordovas J., Coletta D., Parra O., Klimentidis Y., Mandarino L., Moysés-Oliveira M., Tempaku P., Andersen M., Tufik S., Lancaster E., Singh M., Tusié-Luna M., Aguilar-Salinas C., Ochoa-Guzmán A., Pereira A., Martinez-Gonzalez K., Bulik C., Group SFSW., 23andMe Inc Research Team ., Latin American Genomics Consortium ., Atkinson E., Giusti-Rodríguez P.