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Samples from 105 unrelated healthy Sherpa in Namche Bazaar and 111 unrelated non-Sherpa in Kathmandu valley from Nepal were used to obtain allele frequency data for 15 short tandem repeat (STR) loci (CSF1PO, D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPOX and vWA) included in the AmpFLSTR Identifiler kit. No deviations from Hardy-Weinberg equilibrium were observed, but only after applying a Bonferroni correction in the case of D5S818 in the Sherpa population and D7S820 in the Kathmandu population. Genetic parameters of forensic interest were calculated and genetic differentiation between the two populations tested.

Original publication

DOI

10.1016/j.forsciint.2006.03.010

Type

Journal article

Journal

Forensic Sci Int

Publication Date

04/07/2007

Volume

169

Pages

234 - 238

Keywords

DNA Fingerprinting, Gene Frequency, Genetics, Population, Humans, Nepal, Polymerase Chain Reaction, Tandem Repeat Sequences, Tibet