Brian D Nicholson
MRCGP MSc (Health Res) DPhil
Associate Professor
- Affiliate Investigator - KPWHRI
- NIHR Academic Clinical Lecturer
- Postdoctoral Fellow - CRUK PPRC
- Associate Editor - Family Practice
- NIHR CRN Regional SPED Lead
- NHS General Practitioner
Contact information
+44 (0)1865 289300
Diagnosis and Cancer in Primary Care
Brian's academic interests include cancer, global health, and evidence-based diagnosis.
His research aims to improve the diagnostic process for patients with symptoms of cancer. This work focusses on understanding symptoms, appropriate test use, and developing clinical pathways. He leads the departmental Cancer Theme that conducts research in four main areas: health records data; implementation science; diagnostic reasoning; and clinical trials and prospective studies. He is Early Detection lead for the CRUK Oxford Cancer Centre investigating community-based multi-cancer early detection testing.
He currently supervises 4 full time DPhil students, 2 part time EBHC students, one postdoc and one ACF. He is a GP in Oxford City.
Key publications
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Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study.
Journal article
Nicholson BD. et al, (2023), Lancet Oncol, 24, 733 - 743
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Early diagnosis of cancer: systems approach to support clinicians in primary care
Journal article
Black GB. et al, (2023), BMJ (Clinical research ed.), 380
Recent publications
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Personal and organisational health literacy in the non-specific symptom pathway for cancer: An ethnographic study.
Journal article
Black GB. et al, (2024), Health Expect, 27
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Diagnostic yield from symptomatic gastroscopy in the UK: British Society of Gastroenterology analysis using data from the National Endoscopy Database.
Journal article
Beaton DR. et al, (2024), Gut