Febrile illness in high-risk children: a prospective, international observational study.
van der Velden FJS., de Vries G., Martin A., Lim E., von Both U., Kolberg L., Carrol ED., Khanijau A., Herberg JA., De T., Galassini R., Kuijpers TW., Martinón-Torres F., Rivero-Calle I., Vermont CL., Hagedoorn NN., Pokorn M., Pollard AJ., Schlapbach LJ., Tsolia M., Elefhteriou I., Yeung S., Zavadska D., Fink C., Voice M., Zenz W., Kohlmaier B., Agyeman PKA., Usuf E., Secka F., de Groot R., Levin M., van der Flier M., Emonts M., PERFORM consortium None.
To assess and describe the aetiology and management of febrile illness in children with primary or acquired immunodeficiency at high risk of serious bacterial infection, as seen in emergency departments in tertiary hospitals. Prospective data on demographics, presenting features, investigations, microbiology, management, and outcome of patients within the 'Biomarker Validation in HR patients' database in PERFORM, were analysed. Immunocompromised children (