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A 15-year-old Nepalese boy with fever was thought to have enteric fever and started on cefixime. His blood culture grew Salmonella paratyphoid A. On the sixth day, he developed gastrointestinal bleeding, disseminated intravascular coagulation, and later, acute respiratory distress syndrome. He succumbed to his illness despite treatment in the intensive care unit with ceftriaxone, intravenous fluids, and mechanical ventilation. Salmonella paratyphoid A, for which there is no commercial vaccine, may not be a benign disease as perceived, and cefixime that is recommended for enteric fever may be an ineffective choice.

Original publication

DOI

10.1111/j.1708-8305.2008.00238.x

Type

Journal article

Journal

J Travel Med

Publication Date

09/2008

Volume

15

Pages

364 - 365

Keywords

Adolescent, Fatal Outcome, Gastrointestinal Hemorrhage, Humans, Male, Nepal, Paratyphoid Fever, Respiratory Distress Syndrome, Salmonella paratyphi A