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Found 177 matches for

Tracking resistance: Mapping the spread of drug-resistant malaria

On World Mosquito Day, Dr Lucy Harrison, postdoctoral researcher at Oxford’s Infectious Diseases Data Observatory (IDDO) at the Centre for Tropical Medicine and Global Health, reflects on the global impact of the mosquito and her research into malaria drug resistance.

Study finds giving pregnant women cash transfers cuts infant mortality in half

A new study by Associate Professor Dennis Egger (Department of Economics and Centre for the Study of African Economies, University of Oxford) and researchers at the University of California, Berkeley reveals that giving unconditional cash transfers to pregnant women in rural Kenya significantly reduces infant and child mortality.

AMR surveillance project in Nigeria delivers life-saving impacts

A research project led by the Ineos Oxford Institute for antimicrobial research (IOI) to study the cause and impact of antimicrobial-resistant sepsis in Nigeria has resulted in reduced new-born deaths, improved awareness about neonatal infection prevention amongst parents, and strengthened capacity and training for local doctors. The findings have been published in Nature Communications.

New research finds that ivermectin could help control malaria transmission

A collaborative new study involving KEMRI-Wellcome Trust researchers has highlighted a new way to control malaria transmission. The study found that ivermectin, a drug normally used for neglected tropical diseases, led to a 26% reduction in new malaria infections among children aged 5-15.

Oxford vaccine against deadly Nipah virus granted European Medicines Agency PRIME designation

Co-led by researchers at the Pandemic Sciences Institute, the Nipah virus has been granted PRIME designation. This recognises the vaccine’s potential to address the unmet medical need arising from the devastating Nipah virus disease, which can be fatal in up to 85% of cases.

Ambitious project to develop low-cost genome sequencing for pathogens

A low-cost genome sequencing technique that was used by thousands of laboratories globally to spot COVID-19 variants will be extended to cover all pathogens, in an ambitious new Wellcome Trust-funded project launched today. The ARTIC-2 project is led by the University of Birmingham and brings together researchers from the Democratic Republic of Congo, Ghana and Kenya with expertise in responding to numerous viral threats using genomic surveillance, including recent outbreaks of Ebola virus and Mpox in Africa.

University of Oxford announces new Professorship and Centre for Global Primary Care, with support from Dr Sadok Besrour

Nuffield Department of Primary Care Health Sciences, University of Oxford will expand its work in global primary care with a new centre and professorship, thanks to a generous £8.4 million gift from the Fondation Docteur Sadok Besrour.

Latin-American genetic data available securely to approved researchers worldwide

Genetic data from the largest blood-based prospective study of a Latin-American population are now available securely to academic researchers worldwide through the DNAnexus Trusted Research Environment (TRE).

New study confirms malaria drug is safe for children and could reduce disease spread

A major study in The Lancet Infectious Diseases confirms that single low-dose primaquine is safe and effective in reducing malaria transmission in young children. Analysing data from over 6,000 patients, researchers found it effective even in young children and areas with high malaria burden. The findings support expanding primaquine use to tackle drug-resistant malaria in Africa. A child-friendly formulation is urgently needed to maximise its impact on malaria elimination efforts worldwide.

Study shows urgent change needed to reduce deaths from malaria and meningitis in comatose African children

Results of two parallel studies show that one in four African children hospitalised with malaria and coma have an additional infection, and that giving antibiotics with antimalarials could help reduce death rates of comatose children.

Nearly 500,000 children could die from AIDS-related causes by 2030 without stable PEPFAR programmes, Oxford experts estimate

Oxford experts estimate that 1 million additional children could become infected with HIV and nearly 500,000 children could die from AIDS by 2030, while as many as 2.8 million children could become orphaned in the next five years if US President’s Emergency Plan for AIDS Relief (PEPFAR) programmes are reduced or eliminated.

Addressing healthcare workforce challenges with new research partnership

Researchers from the Nuffield Department of Primary Care Health Sciences are part of a major new research initiative aimed at tackling critical workforce challenges in healthcare, particularly in underserved communities.

KEMRI signs landmark partnership with Wellcome and Oxford

The Kenya Medical Research Institute (KEMRI) has officially entered into a seven-year Memorandum of Understanding (MoU) with Wellcome, a UK-based charitable foundation, and the University of Oxford. The £91 million agreement was signed at the Wellcome headquarters in London, marking a significant boost for medical research and training in Kenya.

Prioritising research to better address high-consequence outbreaks

A new paper published in BMC Medicine analyses research prioritisation approaches for high-consequence pathogens.

60% of hepatitis C patients do not know how they had the disease

A survey at Vietnam's National Hospital for Tropical Diseases found 60% of hepatitis C patients unaware of how they contracted the disease, often diagnosed late. Globally, viral hepatitis causes 3,500 daily deaths, ranking second among infectious killers after tuberculosis.

Study finds previously unidentified genetic determinants of rare disease

A landmark study involving researchers from NDM’s Centre for Human Genetics has identified 69 previously unidentified genetic determinants of rare disease, including uncommon forms of epilepsy and schizophrenia.

Study provides support for WHO guidelines for treating pregnant women with HIV

A new analysis by researchers at Oxford Population Health’s Infectious Disease Epidemiology Unit has provided robust evidence in support of current World Health Organization (WHO) guidelines for treating pregnant women living with HIV. The study is published in Clinical Microbiology and Infection.

IOI awards £5m to Oxford consortium to develop new therapies for drug-resistant tuberculosis

The Ineos Oxford Institute for antimicrobial research (IOI) has awarded £5 million to a group of 17 interdisciplinary researchers from Oxford University to develop new therapies for drug-resistant tuberculosis.

Bangladesh malaria mass vaccine and drug administration trial begins

After more than a year of community engagement and preparation in 100 villages with 12,000 populations across the Chittagong Hill Tracts, the mass malaria vaccine (R21/Matrix M) and drug (DHA, piperaquine, and single low dose primaquine) administration study started on 15 Feb.

Advances in AI can help prepare the world for the next pandemic

In the first study of this kind, PSI and Oxford researchers partner with global colleagues to outline how Artificial Intelligence can transform infectious disease research and save more lives.

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